超声对颈动脉内膜中层厚度与动脉顺应性关系的研究

目的探讨颈动脉内膜中层厚度(IMT)与动脉顺应性之间的关系.方法分别选取正常对照组40例,高血压无斑块组47例和斑块组31例,使用超声多普勒测量颈动脉IMT和血管内径的变化.动脉测试仪同步记录血压和动脉顺应性大动脉弹性(C1),小动脉弹性(C2)].结果内径、IMT在斑块组与无斑块组和对照组间有统计学差异(P＜0.01),而后两组间无差异(P＞0.05);C1,C2在三组之间差异均有显著性(P＜0.05).在无斑块组,C2与IMT呈负相关(r=-0.387),而C1与IMT无相关性.在斑块组,C1,C2均与IMT呈负相关(r分别为-0.479、-0.475).结论颈动脉IMT与动脉顺应性间存在线性关系,联合应用可作为早期评价动脉粥样硬化的指标.

Ultrasonographic research on intima-media thickness of common carotid artery and vascular compliance

Objective: To investigate the relationship between intima-media thickness of the common carotid artery and vascular compliance. Methods: 120 subjects were divided into three groups, 40 normotensive individuals as the control group, 47 subjects in non-carotid artery plaque group, and 33 patients in carotid artery plaque group, IMT and diameter of CCA were measured using HP-5500 ultrasound with a high-resolution probe, blood pressure and artery compliance (C1-large artery, C2-small artery) were detected by using HDI DO-2020. Results: IMT and diameter of the CCA of carotid artery plaque group was markedly increased, compared with control group and non-carotid artery plaque group (P <0.01), but there was no statistical difference between control and non-carotid artery plaque groups (P >0.05). Both C1 and C2 among three groups were significantly different (P <0.05). C2 was negatively associated with IMT of CCA and there was no correlation between C1 and IMT of non-carotid artery plaque group. Both C1 and C2 were negatively associated with IMT in carotid artery plaque group. Conclusions: The linear relation is existed between IMT of CCA and vascular compliance, it should be indicators in the diagnosis of early atherosclerosis by combined using.