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腹膜透析液中头孢尼西钠的稳定性考察
引用本文:华俊彦,朱雅艳,田伟强,戴拥燕.腹膜透析液中头孢尼西钠的稳定性考察[J].中国药业,2007,16(1):12-13.
作者姓名:华俊彦  朱雅艳  田伟强  戴拥燕
作者单位:浙江省丽水市中心医院,浙江,丽水,323000
摘    要:目的 考察头孢尼西钠在25℃和37℃下与腹膜透析液配伍的稳定性。方法 将头孢尼西钠加入腹膜透析液中混合均匀后,用紫外分光光度法在25℃和37℃下于0,1,2,4,6,8h时测定头孢尼西钠的含量,同时记录配伍液的外观变化和pH值。结果 头孢尼西钠配伍液外观、pH值及含量均无明显变化。结论 在25℃和37℃下0—8h内头孢尼西钠可与腹膜透析液配伍使用。

关 键 词:头孢尼西钠  腹膜透析液  稳定性  紫外分光光度法
文章编号:1006-4931(2007)01-0012-02
收稿时间:2006-04-04
修稿时间:2006年4月4日

Study on Stability of Cefonicid Sodium in Peritoneal Dialysis Solution
Hua Junyan,Zhu Yayan,Tian Weiqiang,Dai Yongyan.Study on Stability of Cefonicid Sodium in Peritoneal Dialysis Solution[J].China Pharmaceuticals,2007,16(1):12-13.
Authors:Hua Junyan  Zhu Yayan  Tian Weiqiang  Dai Yongyan
Institution:Hua Junyan, Zhu Yayan, Tian Weiqiang, Dai Yongyan ( Central Hospital of Lishui City, Zhejiang Province, 12shui, Zhejiang, China 323000)
Abstract:Objective To study the compatible stability of cefonicid sodium and peritoneal dialysis solution under 25-37℃. Methods Cefonicid was added to the peritoneal dialysis solution and mixed evenly. The content of cefonicid was measured under 25-37℃ at 0, 1, 2, 4, 6, 8 h by UV-chromatography. The changes of the compatible solution and the value of pH were recorded. Results There were no obvious changes in outward appearance, value of pH and the content of cefonicid in the compatible solution. Conclusion Cefonicid can be used compatiblely with peritoneal dialysis solution under 25- 37℃ within 0- 8 h.
Keywords:cefonicid sodium  eritoneal dialysis solution  stablitiy  UV- chromatography
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