氯诺昔康复合氟哌利多在腹腔镜术后自控静脉镇痛的临床观察

目的:研究氯诺昔康复合氟哌利多用于腹腔镜手术后患者自控静脉镇痛的临床效果.方法:选择60例插管全麻下行腹腔镜胆囊切除术患者随机分成三组,每组20例:T组为曲马多1000mg,L组氯诺昔康40mg,LF组氯诺昔康40mg 氟哌利多5mg:三组均加生理盐水至总量100mg,所有患者均不用首次剂量,在术后接镇痛泵持续静脉输注2ml/h,自控剂量为0.5ml,锁定时间为15min.观察并记录术后4h、12h、24h、48h的视觉模拟评分法(VAS)、镇痛总体评价和不良反应的发生情况.结果:LF组在术后4h、12h、24h、48h的VAS评分和镇痛总体评分明显优于T组和L组(P＜0.05),而T组和L组之间无明显差异(P＞0.05);术后恶心呕吐发生率LF组明显低于另两组,而L组又低于T组(P＜0.05),其他不良反应差异无显著意义(P＞0.05).结论:氯诺昔康复合氟哌利多用于患者自控静脉镇痛效果良好,术后恶心呕吐等副作用少,是腹腔镜手术后镇痛治疗的良好选择.

Clinical Observation on Postoperative Analgesia of Self-control by Lornoxicam Complex Droperidol after Celioscope

Objective: To research the clinical effect of Postoperative analgesia of self-control by Lornoxicam complex Droperidol after celioscope.Method: 60 patients who were made cholecystectomy on celioscope in General anesthesia were divided tree groups randomly,each group was 20 cases: T group was Tramadol 1000mg,L group was Lornoxicam 40mg,LF group was Lornoxicam 40mg+ Droperidol 5mg,all patients added to 100 mg normal saline solution and did not use first dosage,used analgesia pump to inject continual in vein 2ml/h,self-control 0.5ml,locked time 15 min.,and noted VAS of 4h,12h,24h,48h,noted analgesia estimate and badness reflection.Result: VAS of 4h,12h,24h,48h postoperative in LF group and the analgesia estimate were better than that in the T group and L group(P<0.05),but T group was not difference with L group(P>0.05),the incidence rate of vomit postoperative in LF group was lower than that the another group,but L group was lower than that the T group(P<0.05),another badness reflection were not significance(P>0.05).Conclusion: Lornoxicam complex Droperidol use in self-control veil analgesia,it is less in side-effect and it is a good choice in chioscope operation.