Severity and duration of mental deficiency symptoms after intravenous administration of propofol |
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Authors: | S. Seidl R. Hausmann J. Neisser H. -D. Janisch P. Betz |
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Affiliation: | 1.Institute for Forensic Medicine,University Erlangen-Nürnberg,Erlangen,Germany;2.Surgery for Gastroenterology,Erlangen,Germany |
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Abstract: | The severity and duration of cognitive performance capacity deficits after intravenous administration of propofol were determined using the validated psychological test procedure syndrome short test (SKT), a simple reaction test and original driving licence exam questions. The test battery was performed before, immediately after, as well as 1 and 2 h after propofol administration in 23 persons. Immediately after propofol anaesthesia, six individuals had a slight performance loss, and four subjects showed mild deficits, consistent with medium organic neuropsychologic disorder or dementia. The status of the subjects rapidly changed for the better, and 2 h after propofol anaesthesia, only one person (4%) showed slight deficits of memory and attention. Therefore, it is suggested that patients refrain from any participation in road traffic for at least 2 h after propofol anaesthesia. Driving a car should not be admitted until an interval of 6 h has elapsed. |
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Keywords: | Propofol Narcotics Deficiency symptoms Memory Attention Driving ability |
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