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乳腺癌保乳术后正向与逆向调强放疗计划的比较
引用本文:孙涛,卢洁,尹勇,刘同海,陈进琥,林秀桐,朱健,白瞳,刘波. 乳腺癌保乳术后正向与逆向调强放疗计划的比较[J]. 中华放射医学与防护杂志, 2009, 29(4): 401-404. DOI: 10.3760/cma.j.issn.0254-5098.2009.04.015
作者姓名:孙涛  卢洁  尹勇  刘同海  陈进琥  林秀桐  朱健  白瞳  刘波
作者单位:山东省肿瘤医院放射物理室,济南,250117
摘    要:目的 比较乳腺癌调强放疗计划的正向和逆向2种设计模式的区别。方法 针对6例左侧乳腺癌保乳术后的患者应用Pinnacle37.4f计划系统,分别设计正向和逆向调强放疗计划,在射野方向相同、保证处方剂量线包绕95%靶区体积的前提下,比较2种计划的剂量体积直方图参数和加速器总跳数。结果 2种调强计划相比,正向及逆向调强计划的计划靶区体积适形度指数值分别为0.67±0.06和0.66±0.06(t=2.423,P>0.05),均匀性指数值分别为(28.2±6.0)%和(26.1±6.8)%(t=2.164,P>0.05);左肺V20分别为(18.7±3.3)%和(17.0±2.8)%(t=5.087,P<0.05),V30分别为(15.5±3.0)%和(14.0±2.6)%(t=7.272,P<0.05);心脏V30分别为(4.1±3.1)%和(3.5±2.5)%(t=1.916,P>0.05);机器跳数分别为(262±5)MU和(308±14)MU(t=7.515,P<0.05)。结论 与正向调强放疗计划相比,乳腺癌逆向调强计划中靶区适形度和均匀性无差别,左肺受量降低,心脏受量无差别;但机器跳数显著增加,增加了机器的磨损和治疗实施时间。

关 键 词:乳腺肿瘤  乳房保留术  正向调强放射治疗  逆向调强放射治疗
收稿时间:2009-04-24

Comparison of forward and inverse intensity modulation radiotherapy planning for breast cancer after breast-conservative surgery
SUN Tao,LU Jie,YIN Yong,LIU Tong-hai,CHEN Jin-hu,LIN Xiu-tong,ZHU Jian,BAI Tong and LIU Bo. Comparison of forward and inverse intensity modulation radiotherapy planning for breast cancer after breast-conservative surgery[J]. Chinese Journal of Radiological Medicine and Protection, 2009, 29(4): 401-404. DOI: 10.3760/cma.j.issn.0254-5098.2009.04.015
Authors:SUN Tao  LU Jie  YIN Yong  LIU Tong-hai  CHEN Jin-hu  LIN Xiu-tong  ZHU Jian  BAI Tong  LIU Bo
Affiliation:Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China;Department of Radiation Physics, Shandong Tumor Hospital, Jinan 250117, China
Abstract:
Keywords:Breast neoplasm   Breast-conservative surgery   Forward intensity-modulated radiotherapy   Inverse intensity-modulated radiotherapy
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