银康颗粒剂治疗银屑病252例疗效观察

目的:观察纯中药制剂银康颗粒剂治疗银屑病的,临床疗效及治疗前后患者血粘度的变化。方法:将382例患者随机分为2组,治疗组252例应用银康颗粒剂治疗,对照组130例应用复方青黛胶囊治疗;对治疗组部分病例(212例)治疗前后血粘度指标进行观察。结果:治疗组治愈148例,好转82例,未愈22例,总有效率为91.12％;对照组治愈51例,好转46例,未愈33例,总有效率为74.62％,2组总有效率比较,差异有非常显著性意义(P<0.01)。治疗组患者治疗前后全血粘度差异无显著性意义(P>0.05),血浆粘度差异有显著性意义(P<0.05)。结论:风邪外袭、血虚生风、气滞血瘀是致病的主要原因。治疗应以清热祛风与养血活血并举。

Treatment of Psoriasis by Yinkang Granules: A Clinical Observation of 252 Cases

Objective: To observe the curative effect of Yinkang Granules (YG) for psoriasis and the change of blood viscosity (BV) after treatment. Methods: 382 cases were allocated to 2 groups randomly, the treatment group (252 cases) was treated by YG and the control group (130 cases) by compound Indigo Naturalis Capsule. The BV of 212 cases in treatment group were observed before and after treatment. Results: In treatment group, 148 cases were cured, 82 cases improved and 22 cases ineffective after treatment, the total effective rate being 91. 27% , and 51, 46, 33 and 74. 62% respectively ( P < 0. 01) in control group. In treatment group, the whole BV showed no significant difference ( P > 0.05) after treatment, while the viscocity of plasma showed significant difference (P < 0. 05) . Conclusion: It is considered that the exogenous wind invasion, blood - deficiency leading to generation of wind, stagnation of qi and blood - stasis are the main cause of the disease. The therapeutic principles of clearing heat, expelling wind, nourishing blood and activating blood circulation should be applied simultaneously.