成年人脂肪肝的筛查及相关危险因素分析

目的探讨成年人脂肪肝的患病率及相关危险因素。方法按照随机分层整群抽样方法对2120例来自上海、无锡、苏州、常州地区,在我院体检的18岁以上成年人进行调查,内容包括询问病史、体格检查、血生化检验、腹部彩色B超等,统计脂肪肝的患病率并分析相关危险因素。结果2120例成人中,共筛查出脂肪肝患者449例,脂肪肝的检出率是21.2%;按年龄分层后,中年人群脂肪肝的检出率为28.6%,明显高于中年以下人群(15.1%)和老年人群(13.5%),与502例正常对照组相比较,脂肪肝组的体重指数(BMI)、血压(SBP/DBP)、空腹血糖(FPG)、血甘油三酯(TG)、血总胆固醇(TC)、低密度脂蛋白(LDL)、血尿酸(UA)均值,明显高于正常对照组,差异有显著性(P<0.01);脂肪肝组超重或肥胖、高血压病、2型糖尿病、高血脂症及肝功能异常的患病率明显高于正常对照组(P<0.01)。结论中年人群脂肪肝的患病率较高,脂肪肝的发生与超重或肥胖,高血压、高血糖、高血脂等代谢紊乱危险因素的聚集密切相关。

Prevalence and Analysis of Cogrelative Risk Factors of Fatty Livet in Adults

Objective To investigate the prevalence and correlative risk factors of fatty liver in adult persons. Methods A crosssectional survey with multiple-stages and random samplings was performed in 2 120 adult persons aged over 18 who underwent health check up from Shanghai、Suzhou、Wuxi、Changzhou areas.Questionaire、body check up、body weight index、blood pressure、blood glucose、triglyceride、total cholesterol、blood uric acid and real-time ultrasonography criteria of liver were measured.The prevalence rate of fatty liver was calculated and analyzed correlative risk factors of fatty liver.Results 449 cases of fatty liver were calculated in 2 120 adult.The prevalence of fatty liver was 21.2%.The prevalence of fatty liver in middle-aged persons was 28.6%.It was significantly higher than in under middle-aged persons（15.1%） and elderly（13.5%）.The body weight index（BMI）,blood pressure（SBP/DBP）,blood glucose（FPG）,triglyceride（TG）,total cholesterol （TC）,LDL,and blood uric acid were significantly higher in fatty liver group than in normal controls group（P〈0.01）.The prevalence of over weight/obesity,hypertension,diabetes mellitus,dyslipidemia and abnormal of liver function were significantly higher in fatty liver group than in normal controls group（P〈0.01）.Conclusion The prevalence of fatty liver was higher in middle-aged persons.The formed of fatty liver might be closely related to the clustering risk factors in metabolic disorders as over weight/obesity,hypertension,hyperglycemia,dyslipidemia.