刺激条件的改变对丘脑束旁核痛兴奋单位和痛抑制单位放电的影响

<正> 许多资料报导,丘脑束旁核与痛觉的感受有密切的关系。本实验室以往的工作表明,丘脑束旁核内存在着痛兴奋单位(Pain-excitation unit,PEU)和痛抑制单位(Pain-inhibition unit,PIU),当伤害性刺激作用于机体时可引起PEU活动增

INFLUENCE OF VARIOUS STIMULATIONS ON PAINEXCITATION AND PAIN-INHIBITION UNIT DISCHARGES IN N. PARAFASCICULARIS OF THE THALAMUS

The unit discharges in n. parufascicularis of the thalamus in albino rats were studied with glass microelectrode. The following results were obtained. 1.The means of threshold and weak stimulation intensities were found to be 12.67 v and 7.87 v for PEU (pain-excitation unit), 12.11 v and 8.55 v for PIU (pain-inhibition unit) respectively. The statistical difference between the thresholds or weak stimulation intensities of PEU and PIU was not signigicant (P>0.05). 2. The duration of evoked responses of PEU or PIU was short with weak stimulus and long with strong stimulus. The response patterns of these 2 kinds of units could not be changed by altering the stimulation intensity. 3. Effects of stimulating the ipsilateral and contralateral sciatic nerves on PEU and PIU were similar. Change of stimulating duration or repetitive stimulation did not alter the discharge pattern of PEU and PIU. From the results of our experiments, it is believed that PEU and PIU may be two different types of neurons.