| 光刺激对视觉功能区的^18F-FDG再分布的影响 |
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| 引用本文： | 徐佩,郭万华,张剑戈,申景涛,贾支俊,张颖.光刺激对视觉功能区的^18F-FDG再分布的影响[J].东南国防医药,2009,11(3):214-217. |
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| 作者姓名： | 徐佩 郭万华 张剑戈 申景涛 贾支俊 张颖 |
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| 作者单位： | 1. 南京大学医学院附属鼓楼医院核医学科,江苏南京,210008
2. 上海交通大学基础医学部生物医学工程教研室,上海,200025 |
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| 基金项目： | 南京市卫生局医学重点项目 |
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| 摘 要： | 目的研究光刺激和时间延迟因素对脑的视觉功能区^18F-FDG代谢影响。方法应用PET/CT对21例正常人脑行^18F-FDG PET显像,注射后1h按有无光刺激分成二组,并于注射后2h后分别再次采集脑部图像,分析光刺激和时间延迟因素是否会引起^18F-FDG在脑内的再分布。结果在给予光刺激后,大脑的布劳德曼（Brodmann）17、18、19分区、中枕回、楔叶及舌回区域对称性代谢增高,而在丘脑、前连合、胼胝体、尾状核及海马部位则对称性降低。在未受光线视觉刺激研究组,早期相和延迟相未见视觉传导通路上脑区代谢变化。结论^18F-FDG在引入体内后,如果未有光线刺激,其视觉功能区的代谢分布尚可保持相对稳定;反之,光线刺激可引起^18F-FDG在脑内的再分布及视觉功能区的代谢变化。
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| 关 键 词： | 视觉功能区 光刺激 ^18F-FDG PET/CT |
The comparative study of the photostimulation and time factor to the redistribution of 18F-FDG in brain visual functional area |
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| XU Pei,GUO Wan-hua,ZHANG Jian-ge,SHEN Jing-tao,ZHANG Ying.The comparative study of the photostimulation and time factor to the redistribution of 18F-FDG in brain visual functional area[J].Journal of Southeast China National Defence Medical Science,2009,11(3):214-217. |
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| Authors: | XU Pei GUO Wan-hua ZHANG Jian-ge SHEN Jing-tao ZHANG Ying |
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| Institution: | XU Pei1,GUO Wan-hua1,ZHANG Jian-ge2,SHEN Jing-tao1,ZHANG Ying1(1.Department of Nuclear Medicin,Nanjing Drum Tower Hospital,Nanjing 210008,China.2.Biomedical Engineering Teaching , Researching Section,the Preclinical Medicine Department of Shanghai Jiao Tong University,Shanghai 200025,China) |
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| Abstract: | Objective To study the effect of photostimulation and time delay to the redistribution of 18F-fluorodeoxyglucose(18F-FDG) in brain visual functional area.Methods 18F-FDG PET/CT imaging data acquired from 21 healthy people were collected.They were divided into two groups according to whether there was photostimulation and images were collected in early phase(1h after injection) and lag phase(2h after injection) respectively.With statistics based by pixel,paired t-test was used in brain functional region betw... |
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| Keywords: | 18F-FDG PET/CT |
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