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T lineage lymphocytes in nude mice born from homozygous nu/nu parents.
Authors:F. Loor,Heidi Amstutz,Lena-Britt H  gg,Kathleen S. Mayor,G. E. Roelants
Affiliation:F. Loor,Heidi Amstutz,Lena-Britt Hägg,Kathleen S. Mayor,G. E. Roelants
Abstract:T lineage cells are found in the spleen of neonatal nu/nu mice born from nu/nu x nu/nu matings, and also in old, healthy nude mice obtained from the usual nu/+ x nu/nu matings. Their presence in neonatal nude mice which were never in contact with mother or normal littermate thymus products shows that commitment of stem cells towards the T lineage does not require the influence of the thymus.
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