T lineage lymphocytes in nude mice born from homozygous nu/nu parents. |
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Authors: | F. Loor,Heidi Amstutz,Lena-Britt H gg,Kathleen S. Mayor,G. E. Roelants |
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Affiliation: | F. Loor,Heidi Amstutz,Lena-Britt Hägg,Kathleen S. Mayor,G. E. Roelants |
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Abstract: | T lineage cells are found in the spleen of neonatal nu/nu mice born from nu/nu x nu/nu matings, and also in old, healthy nude mice obtained from the usual nu/+ x nu/nu matings. Their presence in neonatal nude mice which were never in contact with mother or normal littermate thymus products shows that commitment of stem cells towards the T lineage does not require the influence of the thymus. |
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