APSIC预防中心静脉导管相关性感染指南在ICU的实践

目的 探讨基于亚太感染控制协会(APSIC)预防中心静脉导管相关性血流感染指南在重症医学科患者中的实践效果.方法 根据APSIC指南,结合参与研究的重症医学科实际情况,找出最佳循证证据及最佳临床实践路径,设计干预方案.选取观察组139例,对照组127例,观察组基于APSIC预防中心静脉导管相关性感染(CRBSI)指南进行干预,对照组采用常规操作.分析两组干预措施对预防CRBSI的效果,数据采用SPSS 20.0统计软件进行分析.结果 观察组与对照组是否发生CRBSI对照分析显示,形成完整诊断的CRBSI差异无统计学意义(P=0.248),疑似CRBSI的对比差异有统计学意义(P=0.022),静脉血栓(P=0.338)、其他并发症(P=0.138)差异无统计学意义.结论 基于APSIC指南的循证干预并不能明显改善使用中心静脉导管过程中发生的并发症,但是,基于指南的实践干预组发生CRBSI的患者数少于对照组,说明基于APSIC指南的实践干预是有价值的,特别是Ⅰ级证据.

An evidence-based on the APSIC guide for prevention of catheter-related blood stream infections in ICU patients: A randomized trial.

Objective To study the effect of Asia Pacific Society of Infection Control (APSIC) guidelines on the prevention of catheter-related blood stream infection (CRBSI) in ICU.Methods We design the intervention program combined the actual situation of the ICU based on the APSIC guidelines.From June 2016 to December 2016, 139 cases in the experimental group and 127 cases in the control group were random selected according to the requirements.This effect on CBRSI was analyzed.Results There was no significant difference in complete diagnosis of CRBSI (P=0.248), venous thrombosis (P=0.338) or other complications (P=0.138) between the 2 groups;but significant difference in suspected CRBSI (P=0.022).Conclusion In this study, complications of central venous catheters were without significantly improvement