帕金森病临床诊断现状分析

对 94 4例门诊帕金森病 (Parkinsondisease,PD)患者的既往诊断情况进行调查 ,分析误诊原因。 94 4例患者在病后 <0 .5年确诊者占 35.1% ,在病后 0 .5～ <1.0年内确诊者为 2 6 .3% ,在病后 1.0～ <2 .0年内确诊者为17.6 % ,在病后 2 .0～ <3.0年内确诊者为 8.5% ,在患病≥ 3.0年后确诊者为 12 .5%。发病年龄 <4 0岁的患者规定为早发型帕金森病 ( young onsetParkinsondisease,YOPD) ,发病年龄≥ 4 0岁者规定为普通型PD。震颤型患者中YOPD确诊时间为 ( 1.7± 1.9)年 ,普通型PD确诊时间为 ( 1.4± 1.7)年 ,两者比较无明显差异。僵直型患者中YOPD确诊时间为 ( 2 .6± 2 .4 )年 ,普通型PD为 ( 1.6± 1.8)年 ,两者比较有显著性差异 (P <0 .0 5)。提示 :僵直型患者中YOPD确诊时间较普通型PD晚

Diagnosis of Parkinson Disease

Altogether 944 cases of Parkinson disease patients were investigated about their experien ce of treatment, and the reasons of misdiagnosis were summed up. Of the 944 cases, 35.1% of them wer e diagnosed within half a year, 26.3% patients were diagnosed between 0.5 to 1 year, 17.6% patients were diagnosed between 1.0 to 2.0 year, 8.5% patients were diagnosed between 2.0 to 3.0 year, while 12.5% patients were diagnosed after 3 years. Some patients were thought to be young-onset Parkinson disease (YOPD) if the illness onset before 40 year old, while other patients were thought to be re gular PD if the illness onset after 40 year old. In the tremor patients, the diagnosis time of YOPD was (1.7± 1.9) years, while the regular one was (1.4 ±1.7) years, the difference was not significant; In the rigidity type patients, the diagnosis time of YOPD was (2.6±2.4) years, while the regular PD was (1.6 ± 1.8) years, the difference was significant. The former's time of diagnosis i s longer than the later's.