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Dramatic Response to Platinum in a Patient with Cancer with a Germline BRCA2 Mutation |
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| Authors: | R Moule A Sohaib R Eeles |
| Institution: | 1. Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281 - S9, 9000 Ghent, Belgium;2. Laboratorio de Procesado de Imagen, ETSI Telecomunicación, Universidad de Valladolid, 47011 Valladolid, Spain;3. Applied Chest Imaging Laboratory (ACIL), Brigham and Women’s Hospital, Harvard Medical School, 1249 Boylston St., Boston, MA 02115, USA;4. Biomedical Image Technologies Laboratory, ETSI Telecomunicación, Universidad Politécnica de Madrid, and CIBER-BBN, Madrid, Spain |
| Abstract: | We present a case of dramatic response of poor prognosis cancer in a lady with a germline mutation in the BRCA2 gene who was exposed to platinum containing chemotherapy. She is cancer-free 10 years’ later. Such cases provide clinical scenarios for the basis of trials of platinum-like agents in individuals with BRCA mutations who develop cancer. |
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