北京市首例输入性传染性非典型肺炎家族内传播的流行病学分析

目的：描述传染性非典型肺炎[严重急性呼吸综合征(SARS)]传播链，以探讨该病在人群中传播的规律和特征。方法：对北京市第一起输入性疫情相关的病例及其密切接触者逐一进行流行病学调查，分析病例之间的关系，并采集相关标本进行实验室检测。结果：2003年3月5日北京市发生第一例输入性SARS病例，并在家庭内和医院造成9人感染，其中2例死亡；指示病例潜伏期为4天，第二代病例潜伏期为平均7天(4～17天)，第三代病例较少，潜伏期为8天。潜伏期越短，发热维持时间越长，病情越重。经及时采取综合控制措施，疫情得到控制。结论：SARS在传播过程中存在家庭及医院聚集性，主要为呼吸道飞沫传播和密切接触传播。

Analysis on the epidemiological features and the transmission of an imported severe acute respiratory syndrome case in Beijing

Objective To explore the characteristics of severe acute respiratory syndrome (SARS) transmission in the population base on analyzing the first imported case and the chains of transmission. Methods For the first imported SARS case and cases who were transmitted by the index case, epidemiological investigations were conducted using the guidelines for surveillance and case investigation issued by the Ministry of Health. Data as the date of onset of symptoms, date of hospitalization, contact history etc. for each of the cases and their close contacts were collected and analyzed. Results The first imported SARS case introduced to Beijing had infected 9 people within the family and at the hospital, with two of whom died of the same disease. The incubation period for that index case was 4 days, and that for the cases considered to be the secondary and tertiary generations were 7 and 8 days, respectively. The shorter the incubation period, the longer the fever would last and clinically more severe. Conclusion One of the epidemiological characteristics of SARS in Beijing was noticed that the disease clustered in families and hospitals. Infection through droplets and close contact has been viewed as the primary mode of transmission.