Specific translocation t(1;3) in acute myelomonocytic leukemia: a further case |
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| Authors: | J M Scheres T W Hustinx J G Haasjes C Haanen |
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| Affiliation: | 1. Department of Human Genetics, Faculty of Medicine, University of Nijmegen, Nijmegen, The Netherlands.;2. Department of Hematology, Faculty of Medicine, University of Nijmegen, Nijmegen, The Netherlands.;1. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA;1. Cytogenetics Unit, Christian Medical College & Hospital, Vellore, Tamil Nadu 632004, India;2. Department of Transfusion Medicine and Immunohematology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India;3. Department of Hematology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India;4. Department of Pathology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India;1. Department of Civil and Environmental Engineering, University of Windsor, Windsor, Canada;2. Laboratory of Applied Inorganic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon |
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| Abstract: | We describe herein a translocation, t(1;3)(p36;q21), that was found in the bone marrow of a patient with acute myelomonocytic leukemia preceded by a long lasting myelodysplastic phase. An identical translocation has been reported in three other myelodysplastic patients. one of whom also developed an acute myelomonocytic leukemia. The possible significance of this specific translocation is briefly discussed. |
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