不同雾化吸入方案对肺切除术后病人排痰的影响

目的 :探讨适用于肺切除术后病人更理想的雾化吸入方案 ,以促进病人有效排痰 ,预防术后肺部并发症。方法 :采用正交设计实验方案 ,4个研究因素即雾化吸入的湿化剂、祛痰剂、解痉药和抗生素 ,每因素为 3个水平 ,选用L2 7(34 )正交设计表 ,按确定的实验方案随机分配给入选病人。观察病人吸入不同雾化液时术后5d内排痰量的变化。结果 :不同方案雾化吸入对术后第 1天排痰量有明显影响 (P <0 .0 5 ) ,雾化吸入生理盐水及加入抗生素可显著增加病人术后第 1天的排痰量(P <0 .0 5 ) ,单纯生理盐水雾化吸入比加用祛痰剂或解痉剂时 ,术后第 1天病人排痰量更大(P <0 .0 5 )。结论 :肺切除术后病人雾化吸入液宜选用单纯生理盐水 ,能更有效地促进病人术后排痰。

Influence of Different Aerosol Inhalation Regimen on Expectoration of Postoperative Patients Underwent Pneumonectomy

Objective: to explore an ideal aerosol inhalation regimen for postoperative patients underwent pneumonectomy, to improve their expectoration effectively and to prevent the postoperative complications of patients. Methods: the orthogonal experimental design was adopted. Altogether 4 research factors including wetting agent, expectorants, antispasmodics and antibiotics were taken in the experiment. L 27 (3 4 ) design table was applied. Patients of different groups were randomly arranged to use different aerosol inhalation regimen. The amounts of sputum expectoration of patients were observed within 5 days after different aerosol inhalation. Results: patients with different regimen aerosol inhalation influenced significantly on their expectoration within the 1st day of post-operation (P<0.05). Those who inhaled with normal saline plus antibiotics expectorated significantly more (P<0.05). Patients with pure normal saline inhalation expectorated more on the 1st day of post-operation than those who inhaled with other regimen (P<0.05). Conclusion: it is suitable for patients underwent pneumonectomy to accept normal saline aerosol inhalation, which could accelerate their postoperative expectoration.