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应用ROC曲线分析cTnT和CK-MB对急性心肌梗死的诊断价值
引用本文:何穗,刘康,龙国文,毛福青.应用ROC曲线分析cTnT和CK-MB对急性心肌梗死的诊断价值[J].西部医学,2009,21(10):1796-1797.
作者姓名:何穗  刘康  龙国文  毛福青
作者单位:1. 湘潭市中心医院检验科,湖南,湘潭,411100
2. 湘潭市中心医院血液室,湖南,湘潭,411100
摘    要:目的应用ROC曲线分析心肌肌钙蛋白T(cTnT)和CK—MB对急性心肌梗死的诊断价值。方法检测心梗组、疑似心梗组和健康对照组的血清cTnT、CK—MB水平,所得数据进行t检验和ROC统计分析。结果心梗组、疑似心梗组和健康时照组的血清cTnT、CK—MB水平两两之间有显著差异。cTnT的ROC曲线下面积为0.918,CK—MB的ROC曲线下面积为0.805,cTnT诊断价值高于CK—MB。结论血清cTnT是诊断急性心肌梗死灵敏而特异的诊断指标,其诊断性能明显优于Ck-MB,CK—MB可作为诊断急性心肌梗死的辅助诊断指标。

关 键 词:急性心肌梗死  心肌肌钙蛋白T  CK—MB  ROC曲线

Assessment of receiver operator character curves on diagnostic value of cTnT and CK-MB in acute moycardial infaction
Institution:HE Sui ,LIU Kang ,LONG Guo-wen , et al ( 1. Department of Laboratory, The Central Hospital of Xiangtan, Xiangtan 411 lOG, Hunan; 2. Department of Hematology, The Central Hospital of Xiangtan , Xiangtan 411100, Hunan)
Abstract:Objective To analyze the cardiac troponin T and CK-MB in the diagnosis value of acute myocardial in- faretion(AMI} by receiver operating characteristic (ROC) curves. Methods cTnT and CK-MB was detected in AMI pa- tients, suspected AMI patients and control group. Results There was significant difference in eTnT and CK-MB level in AMI patients, suspected AMI patients and control group. Area under ROC eurve of cTnT was 0. 918, and area under ROC curve of CK-MB was 0. 805. cTnT has more diagnostic value than CK-MB. Conclusion The eTnT is eonfirmed to be the sensitive and specific for detection of AMI, and the eTnT get the better of the CK-MB in the diagnostic peeuliar performanee, CK-MB is confirmed to be the assistant for detection of acute myocardial infarction.
Keywords:CK-MB
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