Angiolymphoid Hyperplasia With Eosinophilia: A Classic Clinical Presentation With Histologic Features of Angiosarcoma |
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| Authors: | Nathalie C. Zeitouni MDCM FRCPC Sameh Hanna MD Thom R. Loree MD John Brooks MD Richard T. Cheney MD |
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| Affiliation: | Department of Dermatology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. zeitouni@roswellpark.org |
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| Abstract: | BACKGROUND: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease manifested by the proliferation of morphologically distinct endothelial cells. OBJECTIVE: To illustrate by a case report the clinical and varied histopathologic findings of ALHE. METHODS: A 29-year-old woman presented with a clinical picture of ALHE but had several histologic features of angiosarcoma. RESULTS: Management of this patient included repeat biopsies of the lesions, excision of the involved areas, careful histologic examination of the entire specimen, and appropriate follow-up. CONCLUSION: ALHE may present with various histologic features. Knowledge of the spectrum of benign and malignant vascular neoplasms helps manage these challenging cases. |
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