不孕症妇女腹腔液与性激素周期性变化

测量63例不孕症妇女腹腔液量(PF-V),用放射免疫法测定其雌二醇(E_2)、孕酮(P)浓度与血清中E_2、P含量比较。结果表明,PF-V随月经周期而改变,排卵前、后有显著性差异;卵巢上有或无排卵斑周期PF-V差异无显著性。排卵后PF中E_2、P含量较血清中E_2、P含量显著增高并维持1周,有或无排卵斑者PF中E_2、P含量有显著性差异。说明PF-V的变化不依赖于排卵裂孔的存在。PF由卵巢渗出并受卵泡、黄体及激素浓度的影响。

Cyclic Changes of Peritoneal Fluid Volume and Steroid Hormone in Women with Infertility

Peritoneal fluid volume (PFV) and levels of steroid hormones in peritoneal fluid (PF) were measured in 63 women with infertility. PFV was changed during the menstrual cycle. There was significant difference between preovulatory phase and early luteal phase in PFV. There was no significant difference be- tween women with and without a stigma in PFV. Our results indicated that the PFV was not related to stig- ma. The PF 17-beta-estradiol (E_2) and progesterone (P) was increased during the preovulatory phase and reached to its peak at early luteal phase. During early corpus luteum phase, the steriod hormones concentra- tions in PF were significantly higher in plasma, and in women with stigma significantly higher than women without stigma. Our results showed that PF is an ovarian exudation product and changes of PFV depended on follicular activity, corpusluteum vascutarity and hormones concentrations.