A B1‐insensitive high resolution 2D T1 mapping pulse sequence for dGEMRIC of the HIP at 3 Tesla |
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Authors: | Riccardo Lattanzi Christian Glaser Artem V. Mikheev Catherine Petchprapa David J. Mossa Soterios Gyftopoulos Henry Rusinek Michael Recht Daniel Kim |
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Affiliation: | 1. Department of Radiology, Center for Biomedical Imaging, New York University Langone Medical Center, New York, New York, USA;2. Department of Radiology, New York University Langone Medical Center, New York, New York, USA |
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Abstract: | Early detection of cartilage degeneration in the hip may help prevent onset and progression of osteoarthritis in young patients with femoroacetabular impingement. Delayed gadolinium‐enhanced MRI of cartilage is sensitive to cartilage glycosaminoglycan loss and could serve as a diagnostic tool for early cartilage degeneration. We propose a new high resolution 2D T1 mapping saturation–recovery pulse sequence with fast spin echo readout for delayed gadolinium‐enhanced magnetic resonance imaging of cartilage of the hip at 3 T. The proposed sequence was validated in a phantom and in 10 hips, using radial imaging planes, against a rigorous multipoint saturation–recovery pulse sequence with fast spin echo readout. T1 measurements by the two pulse sequences were strongly correlated (R2 > 0.95) and in excellent agreement (mean difference = ?8.7 ms; upper and lower 95% limits of agreement = 64.5 and ?81.9 ms, respectively). T1 measurements were insensitive to B1+ variation as large as 20%, making the proposed T1 mapping technique suitable for 3 T. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc. |
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Keywords: | femoroacetabular impingement MRI hip, cartilage dGEMRIC radial MRI T1 mapping B1+ inhomogeneity |
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