Interleaved variable density sampling with a constrained parallel imaging reconstruction for dynamic contrast‐enhanced MR angiography |
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| Authors: | Kang Wang Reed F Busse James H Holmes Philip J Beatty Jean H Brittain Christopher J Francois Scott B Reeder Jiang Du Frank R Korosec |
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| Institution: | 1. Department of Medical Physics, University of Wisconsin‐Madison, Madison, Wisconsin, USA;2. Global Applied Science Laboratory, GE Healthcare, Madison, Wisconsin, USA;3. MR Research, GE Healthcare, Waukesha, Wisconsin, USA;4. Global Applied Science Laboratory, GE Healthcare, Thornhill, Ontario, Canada;5. Department of Radiology, University of Wisconsin‐Madison, Madison, Wisconsin, USA;6. Department of Biomedical Engineering, University of Wisconsin‐Madison, Madison, Wisconsin, USA;7. School of Medicine, University of Wisconsin‐Madison, Madison, Wisconsin, USA;8. Department of Radiology, University of California, San Diego, San Diego, California, USA |
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| Abstract: | For MR applications such as contrast‐enhanced MR angiography, it is desirable to achieve simultaneously high spatial and temporal resolution. The current clinical standard uses view‐sharing methods combined with parallel imaging; however, this approach still provides limited spatial and temporal resolution. To improve on the clinical standard, we present an interleaved variable density (IVD) sampling method that pseudorandomly undersamples each individual frame of a 3D Cartesian ky–kz plane combined with parallel imaging acceleration. From this dataset, time‐resolved images are reconstructed with a method that combines parallel imaging with a multiplicative constraint. Total acceleration factors on the order of 20 are achieved for contrast‐enhanced MR angiography of the lower extremities, and improvements in temporal fidelity of the depiction of the contrast bolus passage are demonstrated relative to the clinical standard. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc. |
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| Keywords: | interleaved variable density sampling constrained reconstruction contrast‐enhanced MR angiography parallel imaging HYCR HYPR |
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