| 阻塞性睡眠呼吸暂停低通气综合征对原发性高血压患者心率变异和血压节律的影响 |
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| 引用本文： | 曾利,史忠,邓国兰,李兵,余林,张冬颖. 阻塞性睡眠呼吸暂停低通气综合征对原发性高血压患者心率变异和血压节律的影响[J]. 高血压杂志, 2010, 0(2) |
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| 作者姓名： | 曾利 史忠 邓国兰 李兵 余林 张冬颖 |
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| 作者单位： | 中国人民解放军第三军医大学附属新桥医院急救部;重庆医科大学附属第一医院心内科;重庆医科大学睡眠呼吸障碍诊疗中心; |
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| 基金项目： | 重庆市卫生局课题(渝05-2-159) |
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| 摘 要： | 目的观察阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对原发性高血压(EH)患者心率变异和血压节律的影响,探讨高血压合并OSAHS患者自主神经功能改变,及OSAHS与血压节律间的关系。方法高血压合并OSAHS患者(EH+OSAHS组)80例,单纯OSAHS患者(OSAHS组)70例,单纯高血压患者(EH组)72例,健康对照(对照组)65例,所有受试对象均进行多道睡眠、24h动态血压和动态心电图监测,分析比较各组昼夜心率变异时域和频域差异,观察昼夜平均动脉压值与非杓型血压和晨峰血压发生率。结果EH+OSAHS组与OSAHS组昼、夜24h内每5min节段平均常RR间期标准差(SDANN),昼、夜低频功率均较EH组与对照组显著增高(均P<0.05),提示昼夜交感神经均显著兴奋;EH+OSAHS组与OSAHS组夜间全程RR间期差值的均方根(rMSSD)、夜间高频功率均较EH组与对照组显著降低(均P<0.05),提示夜间迷走神经活性受抑。EH+OSAHS组与OSAHS组夜间低频与高频之比(L/H)均较EH组与对照组显著增高;4组中,EH+OSAHS组的夜间收缩压和舒张压最高。晨峰血压发生率和非杓型高血压发生率在对照组、E...
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| 关 键 词： | 阻塞性呼吸睡眠暂停低通气综合征 高血压 心率变异 血压节律 |
Changes of Heart Rate Variability, Blood Pressure Rhythm in Hypertensive Patients with Obstructive Sleep Apnea-hypopnea Syndrome |
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| ZENG Li,SHI Zhong,DENG Guo-lan,LI Bing,YU Lin,ZHANG Dong-ying.. Changes of Heart Rate Variability, Blood Pressure Rhythm in Hypertensive Patients with Obstructive Sleep Apnea-hypopnea Syndrome[J]. Chinese Journal of Hypertension, 2010, 0(2) |
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| Authors: | ZENG Li SHI Zhong DENG Guo-lan LI Bing YU Lin ZHANG Dong-ying. |
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| Affiliation: | ZENG Li1,SHI Zhong1,DENG Guo-lan2,LI Bing3,YU Lin3,ZHANG Dong-ying2. 1. Department of Emergency,the Second Affiliated Hospital of the Third Military Medical University,Chongqing 400037,2. Department of Cardiology,the First Affiliated Hospital of Chongqing Medical University 3. Department of Otorhinolaryngology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China |
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| Abstract: | Objective To study the impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) on heart rate variability (HRV), blood pressure rhythm in patients with hypertension as well as the relationship between OSAHS and autonomous nerve system.MethodsTwo hundred eighty-seven middle-aged subjects divided into four groups according to the absence or presence of OSAHS with and without hypertension.OSAHS patients with hypertension (EH+OSAHS group, n=80); OSAHS patients without hypertension (OSAHS group, n=70); Hypert... |
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| Keywords: | Obstructive sleep apnea-hypopnea syndrome Hypertension Heart rate variability Blood pressure rhythm |
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