| 乙型肝炎病毒前S2抗原、核心抗体IgM与其五项指标联合检测的意义 |
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| 引用本文： | 郝繁运.乙型肝炎病毒前S2抗原、核心抗体IgM与其五项指标联合检测的意义[J].青岛大学医学院学报,2008,44(1):56-58. |
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| 作者姓名： | 郝繁运 |
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| 作者单位： | 宁阳中医院检验科,山东,宁阳,271400 |
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| 摘 要： | 目的 探讨乙肝病毒前S2抗原(PreS2-Ag)、乙肝病毒核心抗体IgM(HBcAb-IgM)与乙肝五项指标联合检测的临床意义.方法 采用ELISA法对618例标本进行乙肝五项指标和PreS2-Ag及HBcAb-IgM检测.结果 乙肝五项指标中HBeAg阳性率最低(3.56%),HBsAg阳性率较高(8.25%),HBcAb阳性率最高(43.37%).PreS2-Ag的阳性率(6.63%)高于HBeAg而低于HBsAg.在HBsAg阳性组中,PreS2-Ag阳性率为80.39%,HBsAg阴性组中无1例PreS2-Ag阳性.PreS2-Ag在"大三阳"组中阳性率为90.91%(10/11),在"小三阳"组中阳性率为95.23%(20/21),在"双阳"组(HBsAg、HBcAb阳性)中阳性率为58.33%(7/12).HBcAb-IgM的阳性率较低(0.49%).结论 PreS2-Ag比HBeAg更敏感地反映了病毒的复制情况,PreS2-Ag、HBcAb-IgM与乙肝五项指标联合检测并利用s/co值能更好地对HBV感染者进行临床分析.
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| 关 键 词： | 肝炎病毒 乙型 前S2抗原 病毒核心蛋白质类 实验室技术和方法 |
| 文章编号： | 1672-4488(2008)01-0056-03 |
| 修稿时间： | 2007年5月8日 |
COMBINED DETECTION OF HEPATITIS B VIRUS Pre-S2-Ag,HBcAb-IgM AND HEPATITIS B VIRUS FIVE MARKINGS |
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| HAO FAN-YUN.COMBINED DETECTION OF HEPATITIS B VIRUS Pre-S2-Ag,HBcAb-IgM AND HEPATITIS B VIRUS FIVE MARKINGS[J].Acta Academiae Medicinae Qingdao Universitatis,2008,44(1):56-58. |
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| Authors: | HAO FAN-YUN |
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| Institution: | HAO FAN-YUN (Ningyang Hospital of Traditional Chinese Medicine,Ningyang 271400,China) |
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| Abstract: | Objective To evaluate the clinical significance of combined detection of Pre-S2-Ag,HBcAb-IgM and hepatitis B virus five markings(HBVFMs). Methods HBVFMs,Pre-S2-Ag and HBcAb-IgM were detected in 618 samples by ELISA. Results In HBVFMs,the positive rate of HBeAg was the lowest(3.56%),HBsAg was higher(8.25%),and the highest was HBcAb(43.37%).The positive Pre-S2-Ag(6.63%) was higher than HBeAg(3.56%),but lower than HBsAg(8.25%).In HBsAg-positive group,the positive Pre-S2-Ag was 80.39%,but,no Pre-S2-Ag-positive ... |
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| Keywords: | Hepatitis B virus PreS2-Ag Viral core proteins Laboratory techniques and procedures |
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