保乳手术与改良根治术治疗早期乳腺癌的临床疗效观察

目的：探讨保乳手术与改良根治术治疗早期乳腺癌的临床效果。方法回顾性分析2009年11月～2011年6月本院收治的早期乳腺癌行保乳手术的患者45例为观察组，选择同期行改良根治术的早期乳腺癌患者45例为对照组，比较两组患者的手术效果，术后并发症的发生率，美容效果满意率，5年生存率，局部复发率及远处转移率等情况。结果观察组患者手术时间、术中出血量，住院时间及术后并发症的发生率均少于对照组（P＜0.05）。观察组患者美容效果优良率明显高于其对照组（P＜0.05）；两组患者5年生存率，局部复发率和远处转移率比较，差异无统计学意义（P＞0.05）。结论早期乳腺癌保乳手术治疗效果明显优于改良根治术，具有手术时间短，创伤小，术中出血少，美容效果好及术后并发症少等优点，值得临床推广应用。

Clinical observation of breast-conserving surgery and modified radical mastectomy in the treatment of early-stage breast cancer

Objective To explore the clinical effect of breast-conserving surgery and modified radical mastectomy in the treatment of early-stage breast cancer. Methods 45 cases with early-stage breast cancer patients of breast-conserving surgery from November 2009 to June 2011 in the observation group were analyed.45 patients with early-stage breast cancer patients of modified radical mastectomy in the same period were selected as control group.The effect of surgery,the incidence of postoperative complications,cosmetic results satisfaction rate,5-year survival rate of local recurrence and distant metastasis rates of two groups were observed. Results The operative time,blood loss,hospital stay and postoperative complication rate of the observation group was significantly less than that of control group（P〈0.05）,The cosmetic results excellent rate of observation group was significantly higher than that of control group（P 〈0.05）.There was no statistically significant difference in 5-year survival rate of local recurrence and distant metastasis rate between two groups（P〉0.05）. Conclusion Early breast conserving surgery is better than modified radical mastectomy,with a shorter operative time,less trauma,less bleeding,better cosmetic results and fewer complications,it should be widely conducted.