广西宜州市婚检人群地中海贫血筛查结果分析

目的：了解宜州市婚检人群地中海贫血（地贫）的发生情况。方法采用血细胞分析和血红蛋白电泳对宜州市2011～2012年20830例婚检人员进行地贫筛查。结果20830例婚检者中，血细胞分析检出地贫3310例（15．89％）。血红蛋白电泳检出疑α-地贫1153例（5．54％），其中疑轻型α-地贫1008例、中间型α-地贫57例、疑β复合α地贫88例；疑β-地贫1170例（5．62％）；异常Hb 34例（0．16％）。结论宜州市婚检人群地中海贫血检出率较高，婚前筛查是预防地贫的主要手段。

A Screening for Thalassemia among People Participating in Premarital Examination in Yizhou City,Guangxi

Objective To learn the occurrence of thalassemia among people participating in premarital examination in Yizhou City.Methods The blood and hemoglobin electrophoresis analysis was applied to a screening for thalassemia in 20 830 cases participating from 2011 to 2012 in premarital examination in Yizhou City .Results Among 20 830 cases participating in premarital examination, there were 3 310 cases （ 15.89%） of thalassemia detected by blood analysis.The hemoglobin electrophoresis analysis suggested that there were 1 153（5.54%） suspected α-thalassemia cases,including 1 008 suspected mildα-thalassemia cases,57α-thalassemia intermedia cases and 88 suspected cases of co-inheritance of α-thalassemia andβ-thalassemia,1 170（5.62%） suspected β-thalassemia cases,and 34（0.16%） abnormal Hb cases.Conclusion The prevalence of thalassemia is higher among people participating in premarital examination in Yizhou City .The premarital screening is a primary means for the prevention of thalassemia .