大剂量服用格列美脲、二甲双胍、吡格列酮1例

随着糖尿病患者的逐年增多，降糖药物被广泛的认识和应用，降糖药物的过量应用，可出现诸多副作用。糖尿病患者大剂量服用二甲双胍（格华止）、格列美脲（亚莫利）、吡格列酮（艾汀）后出现急性肾功能衰竭、乳酸酸中毒、消化道出血、脑水肿、呼吸衰竭等一系列并发症，依据药物特性及并发症情况积极选择血液净化治疗及其他抢救措施，成功挽救患者生命，现报道该病例。

Large doses of glimepiride,metformin,pioglitazone one case

With diabetes increasing year by year,hypoglycemic drugs are widely recognized and applied,excessive use of hypoglycemic drugs,there may be many side effects.Diabetic patients taking large doses of metformin （glucophage）,glimepiride（amaryl）,pioglitazone（yiting） after acute renal failure,lactic acidosis,gastrointestinal bleeding,cerebral edema,respiratory failure and a series of complications,according to the characteristics and complications of drug positive blood purification therapy and other select rescue measures,successfully saved the lives of patients,are reported in the following cases.