神经节苷脂联合高压氧治疗新生儿缺氧缺血性脑病的疗效观察

目的：探讨神经节苷脂联合高压氧治疗新生儿缺氧缺血性脑病的疗效。方法80例HIE患儿根据治疗方法不同随机分为观察组和对照组各40例，两组均予常规治疗，观察组同时予神经节苷脂联合高压氧治疗。结果治疗后，两组NABA评分均较治疗前明显升高，且观察组较对照组升高更显著（P＜0.05）。观察组患儿的临床总有效率达92.5%，明显高于对照组（x2=6.893，P＜0.05）。结论神经节苷脂联合高压氧治疗新生儿缺氧缺血性脑病可以提高临床疗效，明显缓解患儿的临床症状，值得推广和应用。

Efficacy of ganglioside and hyperbaric oxygen in treatment of neonatal hypoxic-ischemic encephalopathy

Objective To investigate the effect of ganglioside hyperbaric oxygen in treatment of neonatal hypoxic-ischemic encephalopathy. Methods 80 cases of HIE patients were randomly divided into observation group and the control group of 40 cases, conventional treatment groups were treated between two groups, the observation group added ganglioside and hyperbaric oxygen therapy. Results After treatment, NABA score of both groups significantly increased compared with before treatment, observation group increased more significantly than the control group （P 〈 0.05）. The total effective rate of observation groups was 92.5%, was significantly higher than the control group（χ^2=6.893, P〈0.05）. Conclusion Ganglioside and hyperbaric oxygen in treatment of neonatal hypoxic-ischemic encephalopathy can improve clinical outcomes, significantly relieve symptoms, worthy of promotion and application.