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Evaluation of the Efficiency of the Sample Inactivation Reagent in the Abbott RealTime MTB Assay for Inactivation of Mycobacterium tuberculosis |
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| Authors: | Chao Qi Carole Wallis Vihanga Pahalawatta Andrea Frank Neeshan Ramdin Raquel Viana Klara Abravaya Gregor Leckie Ning Tang |
| Affiliation: | aDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA;bClinical Microbiology Laboratory, Northwestern Memorial Hospital, Chicago, Illinois, USA;cLancet Laboratories, Johannesburg, South Africa;dBARC-SA, Johannesburg, South Africa;eAbbott Molecular, Des Plaines, Illinois, USA |
| Abstract: | The Abbott RealTime MTB assay is a nucleic acid amplification test (NAAT) for the detection of Mycobacterium tuberculosis complex DNA. The sample inactivation procedure used in the assay, consisting of one part sample treated with 3 parts inactivation reagent for 60 min, effectively reduced viscosity and inactivated M. tuberculosis in clinical specimens. |
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