Characterization of Third-Generation-Cephalosporin-Resistant Shiga Toxin-Producing Strains of Escherichia coli O157:H7 in Japan |
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Authors: | Ryuji Kawahara Kazuko Seto Masumi Taguchi Chie Nakajima Yuko Kumeda Yasuhiko Suzuki |
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Affiliation: | aDivision of Bacteriology, Osaka Prefectural Institute of Public Health, Osaka, Japan;bDivision of Bioresources, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan;cHokkaido University, The Global Station for Zoonosis Control, Sapporo, Japan |
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Abstract: | We isolated Shiga toxin-producing Escherichia coli O157:H7 strains resistant to third-generation cephalosporins. The resistant strains harbored blaCMY-2, a plasmid-mediated AmpC β-lactamase. Genotyping of isolates revealed the possible spread of this problematic bacterium. Results suggested the importance of the investigation and surveillance of enterobacteria with plasmids harboring blaCMY-2. |
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