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Characterization of Third-Generation-Cephalosporin-Resistant Shiga Toxin-Producing Strains of Escherichia coli O157:H7 in Japan
Authors:Ryuji Kawahara  Kazuko Seto  Masumi Taguchi  Chie Nakajima  Yuko Kumeda  Yasuhiko Suzuki
Affiliation:aDivision of Bacteriology, Osaka Prefectural Institute of Public Health, Osaka, Japan;bDivision of Bioresources, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan;cHokkaido University, The Global Station for Zoonosis Control, Sapporo, Japan
Abstract:We isolated Shiga toxin-producing Escherichia coli O157:H7 strains resistant to third-generation cephalosporins. The resistant strains harbored blaCMY-2, a plasmid-mediated AmpC β-lactamase. Genotyping of isolates revealed the possible spread of this problematic bacterium. Results suggested the importance of the investigation and surveillance of enterobacteria with plasmids harboring blaCMY-2.
Keywords:
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