Phytochemical screening and antioxidant activity of ethanol extract of Tithonia diversifolia (Hemsl) A. Gray dry flowers |
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Institution: | 1. Laboratório de Pesquisa do Curso de Farmácia, Faculdade de Medicina do ABC, Avenida Príncipe de Gales, 821, Vila Príncipe de Gales, 09060-870, Santo André, SP, Brasil;2. Departamento de Saúde Materno-Infantil, Faculdade de Saúde Pública, Universidade de São Paulo, Brasil |
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Abstract: | ObjectiveTo evaluate the antioxidant activity of extracts of dried flowers of Tithonia diversifolia (Hemsl) A. Gray (T. diversifolia) dry flower-a shrubby plant belonging to the Asteraceae family and very common in Brazil, providing data to help prevent premature aging skin.MethodsThe tests of phytochemical screening included total phenols, tannins, flavonoids, alkaloids and saponins. The active antioxidant was determined by 2,2-diphenyl-1-picryl-hydrazyl method.ResultsThe phytochemical screening of T. diversifolia dry flowers revealed the presence of phenolic compounds (tannins, flavonoids and total phenols), while alkaloids and saponins were not detected. The IC50 values showed a strong antioxidant activity of the plant extracts.ConclusionsTherefore, this study suggests the possibility of using dry flowers extracts of T. diversifolia for the prevention of cell aging, as was shown to have significant antioxidant activity. |
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Keywords: | Antioxidant activity Phytochemical screening |
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