冠状动脉内支架再狭窄相关因素的研究

目的：探讨冠状动脉内支架再狭窄的相关因素，方法：收集行冠状动脉支架术和随访冠脉造影的病例1012例，按随访结果分为支架再狭窄线338例，无再狭窄组674例，并分别进行单因素和多因素分析，比较两组病人临床，病变特征及手术操作相关参数。结果：再狭窄危险性增高的因素包括糖尿病，高血压，复杂病变（B2／C），慢性阻塞性病变，再狭窄病变，长病变，小血管病变，重度狭窄病变和长段支架置入，其相对应的比数比（Odds Ratio)分别为1．42，1．21,1.39,1.84,1.35,1.76,1.92,1.22,1.82，置入Multilink支架相对于Palmaz-Schatz,Wiktor,NIR,S670,Bestent支架再狭窄的危险性减少（OR为0．85），结论：应结合患者的临床特点，病变特征选择冠脉内支架置入的适应征和适当类型的支架。

Assessment of predictors of restenosis after coronary stenting.

Objective To investigate the predictors of in stent restenosis in coronary artery.Methods The data on one thousand and twelve patients who had undergone coronary stent placement and follow up angiography were collected and divided into the restenosis group(338 cases )and non restenosis group(674 cases) in accordance to the angiographic criteria.The clinical lesions and procedural factors of the tow groups were analyzed and compared.Uni variate and multi variate analyses were performed.Results The risk factors for restenosis were:diabetes mellitus,arterial hypertension,complex lesions(B2/C),chronic occlusions,restenotic lesions after PTCA,long lesions,small vessel size,severe stenosis and long length of stented segment.Their odds ratios were 1.42,1.21,1.39,1.84,1.35,1.76,1.92,1.22 and 1.82 respectively.Stent design was also related to restenosis rate.Conclusion Our findings provide some useful information on the appropriate use of coronary stenting.