287例抗菌药物应用情况分析

目的　了解手术科室抗菌药物使用情况及合理性 ,为制定医院抗菌药物使用管理制度提供依据。方法　对手术科室 317份出院病例作回顾性调查。结果　手术科室住院患者抗菌药物使用率达 90 3% ,其中治疗性用药占 30 3% ,预防性用药占 6 3 4% ,混合性用药占 6 3%。抗菌药物使用品种达43种 ,分属 12类 ,总计 770例次。 2 87例中使用单一抗菌药物者占 37 3% ,使用一种以上者占 6 2 7%。在预防用药中以 2联或 3联使用居多 ,占预防用药的 5 2 2 % ,且时间过长。在治疗性用药中仅 11 4%可参考病原菌及药敏试验结果选药。结论　制定抗菌药物使用规范 ,重视病原学检查 ,依据药敏结果选药对减少耐药菌株产生具有极其重要意义。

Analysis of the use of antimicrobial agents by 287 cases

Objective To find out the use of antimicrobial agents in the surgical departments and its rationality so as to provide basis for the formulation of regulations for the use of antimicrobial agents in the hospital. Methods A retrospective investigation was made into 317 cases discharged from the surgical departments. Results The utilization ratio of antimicrobial agents by inpatients from the surgical departments reached 90.3%, including 30.3% for treatment, 63.4% for prevention and 3% for mixed purposes. The use of antimicrobial agents, which could be classified into 12 groups and 43 kinds, amounted to 770 cases(times). 37.3% of the 278 cases used only one kind of antimicrobial agents and 62.7% more than one. The use of 2 kinds or 3 kinds, which also lasted for too long a time, dominated in the use of the agents for prevention, accounting for 52.2%. Only 11.4% of the agents used for treatment could be chosen with reference to pathogenic bacteria and the results of drug sensitive tests. Conclusion Working out regulations for the use of antimicrobial agents, stressing etiological examinations and choosing medicines according to the results of drug sensitive tests are of great significance to the reduction of the occurrence of drug resistant strains.