| 纳米药物粒度分析方法 |
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| 引用本文： | 耿志旺,何兰,张启明,杨永健.纳米药物粒度分析方法[J].药学学报,2012(7):856-862. |
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| 作者姓名： | 耿志旺 何兰 张启明 杨永健 |
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| 作者单位： | 上海市食品药品检验所;中国食品药品检定研究院 |
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| 基金项目： | 国家“重大新药创制”科技重大专项(2011ZX09303-001) |
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| 摘 要： | 纳米药物在研究和应用领域都在快速发展,根据具体纳米药物的特性,运用合理的分析方法来建立质量标准是一项需要深入研究的重要课题。本文综述了可用于纳米药物质量控制的粒度分析方法,考察了几种重要技术的原理、适用范围、优点和不足。结合不同剂型纳米药物的特性,讨论了各方法在纳米药物分析中的应用,为纳米药物的检测和监管提供借鉴。
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| 关 键 词： | 纳米药物 粒度 分析方法 |
Methods for grain size analysis of nanomedicines |
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| GENG Zhi-wang,HE Lan,ZHANG Qi-ming,YANG Yong-jian.Methods for grain size analysis of nanomedicines[J].Acta Pharmaceutica Sinica,2012(7):856-862. |
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| Authors: | GENG Zhi-wang HE Lan ZHANG Qi-ming YANG Yong-jian |
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| Institution: | 1(1.Shanghai Institute for Food and Drug Control,Shanghai 201203,China;2.National Institutes for Food and Drug Control,Beijing 100050,China) |
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| Abstract: | As nanomedicines are developing fast in both academic and market areas,building up suitable methods for nanomedicine analysis with proper techniques is an important subject,requiring further research.The techniques,which could be employed for grain size analysis of nanomedicines,were reviewed.Several key techniques were discussed with their principles,scope of applications,advantages and defects.Their applications to nanomedine analysis were discussed according to the properties of different nanomedicines,with the purpose of providing some suggestions for the control and administration of nanomedicines. |
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| Keywords: | nanomedicine grain size analysis |
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