Genomics and proteomics tools for compound mode-of-action studies in drug discovery |
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| Authors: | Kley Nikolai Ivanov Igor Meier-Ewert Sebastian |
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| Institution: | GPC Biotech, Inc, 610 Lincoln Street, Waltham MA 02451, USA. nikolai.kley@ gpc-biotech.com |
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| Abstract: | A broad range of genomics and proteomics technologies are increasingly being integrated into emerging research fields such as pharmacogenomics, pharmacoproteomics, chemogenomics, chemical genetics, and chemical biology. Here we review applications of genomic and proteomic technologies to drug mechanism-of-action studies and how these are beginning to impact the drug discovery process. |
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