Hypochlorite-promoted transformations of trichothecenes, 3. Deoxynivalenol |
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| Authors: | E P Burrows L L Szafraniec |
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| Affiliation: | U.S. Army Biomedical Research & Development Laboratory, Fort Detrick, Frederick, Maryland 21701-5010. |
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| Abstract: | Treatment of deoxynivalenol [3] in MeOH with hypochlorite bleach containing added NaOH gave rise to a single major product, the 9 alpha, 10 alpha, 12 beta, 13 beta-diepoxy-8,15-hemiketal 4. Thus, the reaction followed a very different course from that observed for verrucarol [2], where rearrangement involving opening of the starting 12,13-epoxide and a haloform-like oxidation took place. |
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