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| 石英晶体微天平技术研究牙釉基质蛋白对牙釉质仿生矿化的诱导作用 | |
| 引用本文： | 王志伟,赵月萍,周长忍,廖国威. 石英晶体微天平技术研究牙釉基质蛋白对牙釉质仿生矿化的诱导作用[J]. 南方医科大学学报, 2009, 29(5): 966 |
| 作者姓名： | 王志伟 赵月萍 周长忍 廖国威 |
| 作者单位： | 1. 暨南大学,医学院口腔医学系,广东,广州,510632 2. 暨南大学,理工学院材料系,广东,广州,510632 3. 暨南大学,附属第一医院口腔科,广东,广州,510632 |
| 摘 要： | 目的 通过石英晶体微天平技术(QCM)在牙釉质表面吸附牙釉基质蛋白,进而研究牙釉基质蛋白对牙釉质表面生物矿化的影响.方法 将牙釉基质蛋白吸附到牙釉质表面上形成蛋白刚性膜,浸入到模拟人工体液中仿生矿化.吸附牙釉基质蛋白的牙釉质经过30d的仿生矿化后,表面出现了羟基磷灰石晶体.结果 牙釉基质蛋白能够很好的诱导羟基磷灰石晶体成核、生长和聚集.结论 牙釉基质蛋白在牙釉质矿化过程中起一定的调控作用,为今后利用生物矿化法治疗龋病提供到了实验基础. |
| 关 键 词： | 石英晶体微天平 牙釉基质蛋白 仿生矿化,牙釉质 |
Role of enamel matrix proteins in inducing biomimetic mineralization of the enamel:a study with quartz crystal microbalance technique |
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| WANG Zhi-wei,ZHAO Yue-ping,ZHOU Chang-ren,LIAO Guo-wei. Role of enamel matrix proteins in inducing biomimetic mineralization of the enamel:a study with quartz crystal microbalance technique[J]. Journal of Southern Medical University, 2009, 29(5): 966 | |
| Authors: | WANG Zhi-wei ZHAO Yue-ping ZHOU Chang-ren LIAO Guo-wei |
| Affiliation: | WANG Zhi-wei1,ZHAO Yue-ping1,ZHOU Chang-ren2,LIAO Guo-wei3 Department of Conservative Dentistry1,Department of Material Science2,College of Science and Technology,Department of Stomatology,First Affiliated Hospital3,Jinan University,Guangzhou 510632,China |
| Abstract: | Objective To investigate the adsorption behavior of enamel matrix proteins (EMPs) on the enamel surface and study their effect on biomineralization of enamel using quartz crystal microbalance (QCM) technique. Methods and Results The EMPs were adsorbed on the enamel surface to form a protein film,which was soaked in simulated body fluid solutions. After 30 days of biomimetic mineralization,the hydroxyapatite nucleation,growth and aggregation occurred with hydroxyapatite crystal formation on the enamel surfac... |
| Keywords: | quartz crystal microbalance enamel matrix proteins biomimetic mineralization enamel |
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