| 环氧化酶与妇科肿瘤的研究进展 |
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| 引用本文： | 彭芸花,代荫梅.环氧化酶与妇科肿瘤的研究进展[J].中国肿瘤,2004,13(5):299-301. |
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| 作者姓名： | 彭芸花 代荫梅 |
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| 作者单位： | 兰州医学院第一附属医院,甘肃,兰州,730000 |
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| 摘 要： | 环氧化酶(COX)是前列腺素(PGs)合成的限速酶,COX-2在多种癌组织中高表达,在肿瘤的发生、发展中起着重要的作用.文章综述国内外COX-2在妇科肿瘤中的表达、调控及其致癌机制方面的研究新进展,为妇科肿瘤的防治提供新的靶目标.
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| 关 键 词： | 环氧化酶 妇科肿瘤 |
| 文章编号： | 1004-0242(2004)05-0299-03 |
The Latest Development of Cyclooxygenase-2 in Gynecologic Oncology |
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| PENG Yun-hua,DAI Yin-mei.The Latest Development of Cyclooxygenase-2 in Gynecologic Oncology[J].Bulletin of Chinese Cancer,2004,13(5):299-301. |
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| Authors: | PENG Yun-hua DAI Yin-mei |
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| Abstract: | Cyclooxygenase(COX) is the key enzyme responsible for the synthesis of prostaglandins(PGs).Many studies have shown high expression of cyclooxygenase-2(COX-2) in a variety of human malignancies and it plays a role in the genesis and development of neoplasms.The gene expression,regulation and carcinogenesis of COX-2 in gynecologic oncology were reviewed ,so as to find a new molecular therapeutic target of gynecologic carcinoma. |
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| Keywords: | cyclooxygenase gynecologic neoplasms |
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