| 头皮脂溢搽剂制备工艺研究 |
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| 引用本文： | 董彦富,祁梅,杨立伦,余利军,贾海.头皮脂溢搽剂制备工艺研究[J].中国药房,2008,19(33):2580-2581. |
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| 作者姓名： | 董彦富 祁梅 杨立伦 余利军 贾海 |
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| 作者单位： | 甘肃省人民医院药剂科 |
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| 摘 要： | 目的:研究头皮脂溢搽剂的制备工艺。方法:采用正交试验设计L9(34),以60%乙醇为溶剂,以盐酸小檗碱含量为考察指标,以提取方法、提取时间、溶剂用量和提取次数为考察因素,确定最佳制备工艺。结果:最佳制备工艺为采用浸渍法,提取时间为48h,60%乙醇用量1500mL,提取次数为2次。结论:本工艺稳定、可行,可为头皮脂溢搽剂的工业化生产提供理论依据。
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| 关 键 词： | 头皮脂溢搽剂 制备工艺 正交试验 盐酸小檗碱 |
Preparation Technology of Chinese Traditional Medicine Seborrhea Liniment |
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| DONG Yan-fu,QI Mei,YANG Li-lun,YU Li-jun,JIA Hai.Preparation Technology of Chinese Traditional Medicine Seborrhea Liniment[J].China Pharmacy,2008,19(33):2580-2581. |
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| Authors: | DONG Yan-fu QI Mei YANG Li-lun YU Li-jun JIA Hai |
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| Institution: | (Dept.of Pharmacy, Gansu Provincial People＇ s Hospital, Lanzhou 730000, China) |
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| Abstract: | OBJECTIVE:To study the preparation technology of Chinese traditional medicine Seborrhea liniment.METHODS:The preparation technology of Seborrhea liniment was optimized by orthogonal experiment design L9(34)using 60% alcohol as solvent with the content of Berberine hydrochloride as index for evaluation and with the extraction method,extraction time,amount of solvent and number of extraction times as factors.RESULTS:The optimum preparation technical conditions were as follows:by impregnating method,the extraction time was 48 h using 1 500 mL alcohol and the extraction frequency was 2 times.CONCLUSION:The preparation technology of Chinese traditional medicine Seborrhea liniment is stable and feasible,and it serves as a theoretical basis for the industrial production. |
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| Keywords: | Seborrhea liniment Preparation technology Orthogonal experiment Berberine hydrochloride |
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