Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism |
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| Authors: | Laura Strada Carlo Gandolfo Massimo Del Sette |
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| Affiliation: | (1) Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy |
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| Abstract: | We report a case of cerebral venous thrombosis (CVT) due to tyrotoxicosis in a patient with methylenetetrahydro-folate-reductase (MTHFR) gene polymorphism C677T, (genotype 677TT), in which discontinuation of intravenous heparin was followed by clinical and radiological worsening despite warfarin treatment. We discuss the relationship between CVT, MTHFR hyperthiroidism and anticoagulant therapy. |
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| Keywords: | Cerebral venous thrombosis Tyrotoxicosis Methylene-tetrahydro-folate-reductase (MTHFR) Heparin Warfarin |
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