| Th17和自身免疫性疾病相关性研究进展 |
| |
| 引用本文： | 梁妍琰.Th17和自身免疫性疾病相关性研究进展[J].国际儿科学杂志,2011,38(1):298-300. |
| |
| 作者姓名： | 梁妍琰 |
| |
| 作者单位： | 内蒙古自治区人民医院小儿科,呼和浩特,010017; |
| |
| 摘 要： | Th17是一种新近发现的CD4+T细胞亚群,它是Th1、Th2家族的新成员.近年来研究发现,Th17能够产生IL-17A、IL-17F、IL-21和IL-22等因子,而这些因子在类风湿关节炎、系统性红斑狼疮、系统性硬化病、炎性肠病、自身免疫性心肌炎等自身免疫性疾病的发生发展中起重要作用.因此,加深对Th17在免疫性疾病进展中的认识将为今后的诊断提供新的依据,Th17及其因子也将成为人类治疗自身免疫性疾病的新靶点.
|
| 关 键 词： | 自身免疫性疾病 |
Advance of the relationship between Th17 and autoimmune diseases |
| |
| LIANG Yan-yan.Advance of the relationship between Th17 and autoimmune diseases[J].International Journal of Pediatrics,2011,38(1):298-300. |
| |
| Authors: | LIANG Yan-yan |
| |
| Abstract: | Th17 is a CD4+ T cell subset that is a new member of Th1 and tH2.Recent studies have shown that it products IL-17A,IL-17F,IL-21 and IL-22,which play an imoortant role in rheumatoid arthritis.systemic lupus erythematosus,systemic sclerosis,inflammatory howel disease.autoimmune myocarditis and other autoimmune diseases.Deepen the understanding of Th17 and Th17 production in the advancement of autoimmune diseases will provide a new basis for future diagnosis.Th17 will become a new target for the treatment of human autoimmune diseases. |
| |
| Keywords: | Th17Th17Autoimmune diseases |
|
|
