| 胸腺肽对小鼠腹腔巨噬细胞释放一氧化氮的影响 |
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| 引用本文： | 嵇扬. 胸腺肽对小鼠腹腔巨噬细胞释放一氧化氮的影响[J]. 中国生化药物杂志, 2001, 22(2): 74-75 |
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| 作者姓名： | 嵇扬 |
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| 作者单位： | 解放军总后勤部卫生部药品仪器检验所, |
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| 摘 要： | 目的研究胸腺肽对小鼠腹腔巨噬细胞释放一氧化氮的影响。方法一氧化氮以Griess试剂测定。结果以多肽计浓度为 83.3～ 333.3μg /ml的胸腺肽能显著抑制小鼠腹腔巨噬细胞一氧化氮释放。 结论胸腺肽对小鼠腹腔巨噬细胞释放一氧化氮的调节可能是其保肝作用机制之一。
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| 关 键 词： | 胸腺肽 一氧化氮 巨噬细胞 |
| 文章编号： | 1005-1678(2001)02-0074-02 |
| 修稿时间： | 2000-06-26 |
Effect of thymopeptide onLPS-induced release of nitric oxide from mouse peritoneal microphase in vitro |
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| Ji Yang. Effect of thymopeptide onLPS-induced release of nitric oxide from mouse peritoneal microphase in vitro[J]. Chinese Journal of Biochemical Pharmaceutics, 2001, 22(2): 74-75 |
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| Authors: | Ji Yang |
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| Abstract: | Purpose The aim is to investigate the effects of thymopeptide on LPS-induced release of nitric oxide (NO) from mouse peritoneal microphase in vitro.Methods NO was detected by Griess reagent.Results Thymopeptide 83.3～333.3 μg/ml reduced NO synthesis and secretion from mouse peritoneal microphase in vitro significantly.Conclusion The effects of thymopeptide on LPS-induced release of NO from mouse peritoneal microphase may be one of mechanisms of its pharmacological effect. |
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| Keywords: | Thymopeptide Nitric oxide Peritoneal microphase |
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