| 热化疗对口腔颌面癌患者细胞毒性T淋巴细胞活性的影响 |
| |
| 引用本文： | 郭军,门昌杰,王升志,高向东,成洲,毛祖彝,王大章. 热化疗对口腔颌面癌患者细胞毒性T淋巴细胞活性的影响[J]. 华西口腔医学杂志, 2007, 25(5): 441-443 |
| |
| 作者姓名： | 郭军 门昌杰 王升志 高向东 成洲 毛祖彝 王大章 |
| |
| 作者单位： | 烟台毓璜顶医院莱山分院,外科,山东,烟台,264003;蓬莱市人民医院,口腔科,山东,蓬莱,265600;烟台毓璜顶医院,口腔颌面外科,山东,烟台,264000;四川大学华西口腔医学院,口腔颌面外科学教研室,四川,成都,610041 |
| |
| 基金项目： | 山东省优秀中青年科学家科研奖励基金 , 山东省自然科学基金 , 广东省医药卫生科研项目 |
| |
| 摘 要： | 目的探讨热化疗对口腔颌面癌患者细胞毒性T淋巴细胞（CTL）活性的影响。方法选取21例口腔颌面癌患者接受热化疗，于第一次治疗前和最后一次治疗后取其外周血行CTL活性检测。结果热化疗后口腔颌面癌患者CTL活性较治疗前大大提高，其差异有统计学意义（P<0.01）。结论热化疗可以提高口腔颌面癌患者CTL的活性，从而增强机体的免疫功能，提高机体抗肿瘤效应。
|
| 关 键 词： | 热化疗 细胞毒性T淋巴细胞 口腔肿瘤 |
| 文章编号： | 1000-1182（2007）05-0441-03 |
| 收稿时间： | 2007-10-25 |
| 修稿时间： | 2007-05-21 |
Influence of thermochemotherapy on the activity of cytotoxic T lymphocyte in oral maxillofacial cancer patients |
| |
| GUO Jun,MEN Chang-jie,WANG Sheng-zhi,GAO Xiang-dong,CHENG Zhou,MAO Zu-yi,WANG Da-zhang. Influence of thermochemotherapy on the activity of cytotoxic T lymphocyte in oral maxillofacial cancer patients[J]. West China journal of stomatology, 2007, 25(5): 441-443 |
| |
| Authors: | GUO Jun MEN Chang-jie WANG Sheng-zhi GAO Xiang-dong CHENG Zhou MAO Zu-yi WANG Da-zhang |
| |
| Affiliation: | 1. Dept. of Surgery, The Branch Hospital of Yantai Yuhuangding Hospital, Yantai 264003, China；2. Dept. of Stomatology, The Penglai People′s Hospital, Penglai 265600, China；3. Dept. of Oral and Maxillofacial Surgery, Yantai Yuhuangding Hospital, Yantai 264000, China； 4. Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China |
| |
| Abstract: | OBJECTIVE: To study the influence of thermochemotherapy on the activity of cytotoxic T lymphocyte (CTL) in peripheral blood of patients with oral maxillofacial cancer. METHODS: Twenty-one subjects with oral maxillofacial cancer were treated by thermochemotherapy, and the activity of CTL in peripheral blood was analyzed. RESULTS: Thermochemotherapy can obviously enhance the activity of CTL (P<0.01). CONCLUSION: Thermochemotherapy can enhance the activity of CTL, thus enhance the patient's immune function. Therefore, it can enhance the antitumor response in whole body. |
| |
| Keywords: | thermochemotherapy cytotoxic T lymphocyte oral tumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《华西口腔医学杂志》浏览原始摘要信息 |
|
点击此处可从《华西口腔医学杂志》下载免费的PDF全文 |
|
