| 何首乌炮制后新产生成分的分离和结构鉴定 |
| |
| 引用本文： | 刘振丽,李林福,宋志前,王淳,张玲,巢志茂. 何首乌炮制后新产生成分的分离和结构鉴定[J]. 中药材, 2007, 30(12): 1505-1507 |
| |
| 作者姓名： | 刘振丽 李林福 宋志前 王淳 张玲 巢志茂 |
| |
| 作者单位： | 1. 中国中医科学院,中医基础理论研究所,北京,100700
2. 中国中医科学院,医学实验中心,北京,100700 |
| |
| 基金项目： | 国家自然科学基金资助项目(30472191)，国家中医药管理局资助项目(04-052P64) |
| |
| 摘 要： | 目的:分离和鉴定何首乌炮制后新产生的化学成分。方法:采用HPLC法确定提取溶剂,用聚酰胺、大孔吸附树脂、ODS柱色谱等方法进行分离纯化,通过理化性质及光谱数据确定化合物结构。结果:新产生的化学成分为5-羟基麦芽酚(Ⅰ)和5-羟甲基糠醛(Ⅱ)。结论:两个化合物为首次从该属植物中分离得到。
|
| 关 键 词： | 何首乌 炮制 5-羟基麦芽酚 5-羟甲基糠醛 |
| 文章编号： | 1001-4454（2007）12-1505-03 |
| 收稿时间： | 2007-06-18 |
| 修稿时间： | 2007-06-18 |
New Chemical Constituents from Radix Polygoni Multiflori after Processing |
| |
| LIU Zhen-li,LI Lin-fu,SONG Zhi-qian,WANG Chun,ZHANG Ling,CHAO Zhi-mao. New Chemical Constituents from Radix Polygoni Multiflori after Processing[J]. Journal of Chinese medicinal materials, 2007, 30(12): 1505-1507 |
| |
| Authors: | LIU Zhen-li LI Lin-fu SONG Zhi-qian WANG Chun ZHANG Ling CHAO Zhi-mao |
| |
| Affiliation: | China Academy of Chinese Medical Science 1. The Institute of Basic Theory;2. Medical Experiment Centra, Beijing 100700, China |
| |
| Abstract: | OBJECTIVE: To study the new chemical constituents from Radix Polygoni Multiflori after processing. METHODS: Various kinds of chromatographic methods were used to deparate the chemical constituents from Radix Polygoni Multiflori after processing. Their structures were determined by NMR and MS spectral data. RESULTS: The two new compounds were 2,3-dihydro-3,5-dihydroxy-6-meth-yl-4 (H)-pyran-4-one(I) and 5-hydruoxymethyl-furfuran(II). CONCLUSION: It is the first time that compound I and 1I were isolated from Polygoni. |
| |
| Keywords: | Radix Polygoni Multiflori Processing 2 3-Dihydro-3 5-dihydroxy-6-methyl-4(H)-pyran-4-one 5-Hydroxymethyl-furfuran |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
