Diagnosis of nasopharyngeal carcinoma |
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Authors: | J K Woo C L Sham |
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Institution: | Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T. |
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Abstract: | The diagnosis of nasopharyngeal carcinoma rests on perceptive symptom analysis, a careful clinical examination, and the selection of appropriate clinical investigations. A high index of suspicion is required. When mirror examination fails to provide a satisfactory view of the nasopharynx, flexible or rigid nasopharyngeal endoscopy is mandatory. Serologic examination of IgA antibodies to Epstein-Barr virus early antigen and viral capsid antigen is helpful in identifying high-risk patients. Biopsy material should be sent fresh to the laboratory for analysis so that special staining can be carried out in cases of doubtful diagnosis. |
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