血仿膜透析器在无肝素透析中的应用研究

目的 探讨急慢性肾功能衰竭伴有高危出血倾向患者行血液透析治疗理想的抗凝方法。方法 在应用血仿膜透析器行无肝素透析前后常规采血测定凝血常规三项常数，按成对资料t检验进行统计学处理。观察透析器及透析管路凝血程度，判断透析器、透析管路有否凝血征象，比较透析前后各项指标。结果 无肝素透析前后血液凝血常规指标变化差异均无显著性（P〉0．05）。透析过程中除1例次因血路建立困难，致透析器凝血，静脉压升高需更换透析器重建血路外，余能顺利完成透析，成功率达98％。结论 血仿膜透析器行无肝素透析对急慢性肾功能衰竭患者全身凝血机制无影响，此方法简单、安全、有效，为抢救急慢性肾功能衰竭伴有高危出血倾向患者行血液透析提供了可靠的方法。

The research on making use of hemophan dialyzer in the application of heparin- free hemodialysis

Objective To explore the substantial results of using comprehensive practical teaching mode and holistic nursing thinking method in the course of teaching fundamentals of nursing science,and then improve the vocational quality and ability of nursing students.Methods Randomly determined two classes as objectives: experiment class and control class.control class was adopt traditional practical teaching mode,experiment class was adopt comprehensive practical teaching mode in small community.Results Ability of standard operation,communication and knowledge were significant higher in experiment class than those of in control class.Conclusions Comprehensive practical teaching mode in small community has actual significance for strengthen the comprehendsive ability of nursing students.