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孕早期子宫颈管脱落滋养细胞的收集与影响因素探讨
引用本文:乔云波,史桂芝,王今锦,孟静,孙晓荣,吴蔚,刘丹茹. 孕早期子宫颈管脱落滋养细胞的收集与影响因素探讨[J]. 现代妇产科进展, 2006, 15(1): 25-27
作者姓名:乔云波  史桂芝  王今锦  孟静  孙晓荣  吴蔚  刘丹茹
作者单位:济南市妇幼保健院,济南,250001
基金项目:济南市科技局资助课题(济科合字2001第015078号)
摘    要:目的:探讨孕早期子宫颈管脱落滋养细胞的收集与影响因素,为进一步的孕早期无创性产前诊断奠定基础。方法:从早孕妇女的宫颈管获取脱落的滋养细胞并探讨影响因素。结果:双取器宫颈管毛刷法获取的阳性率最高;孕5~7周是取材较适宜的时间;妊娠囊下缘至宫颈内口的距离对获取的滋养细胞影响较小。结论:孕早期获取宫颈管脱落滋养细胞是可行的;取材工具,取材孕周对获取孕早期脱落滋养细胞有一定的影响。

关 键 词:产前诊断  妊娠早期  宫颈管  滋养层细胞
文章编号:1004-7379(2006)01-0025-03
收稿时间:2005-08-12
修稿时间:2005-08-12

The collection of fetal trophoblast cells from endocervix and it''''s affecting factors during early pregnancy
Qiao Yunbo, Shi Guizhi, Wang Jinjin, et al. The collection of fetal trophoblast cells from endocervix and it''''s affecting factors during early pregnancy[J]. Current Advances In Obstetrics and Gynecology, 2006, 15(1): 25-27
Authors:Qiao Yunbo   Shi Guizhi   Wang Jinjin   et al
Affiliation:Jinan Maternity and Childcare Hospital ,Jinan 250012
Abstract:Objective: To evaluate the collection of trophoblastic cells and it's affecting factors in endocervical canal during early pregnancy.Methods:Women undergoing first-trimester termination of pregnancy were recruited for endocervical sampling.Collecting instruments,gestational age,and implantation site were discussed.Results:Endocervical cytobrush was the most suitable instrument for acquiring trophoblastic cells;the suitable time for obtaining trophoblastic cell was 5~7 weeks of gestation;the distance from inner cervical canal to gestational sac had no significant effect on acquiring trophoblastic cells.Conclusion:Instrument and gestational age may affect the collection of trophoblastic cells in endocervical canal during early pregnancy.
Keywords:Prenatal diagnosis  Pregnancy trimester  first  Endocervical cannal  Trophoblastic cell  
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