| 两面针根挥发油的抗炎镇痛作用研究 |
| |
| 引用本文： | 周劲帆,覃富景,冯洁,韦柳婷.两面针根挥发油的抗炎镇痛作用研究[J].时珍国医国药,2012,23(1):19-20. |
| |
| 作者姓名： | 周劲帆 覃富景 冯洁 韦柳婷 |
| |
| 作者单位： | 1. 广西医科大学药学院,广西南宁,530021
2. 广西医科大学药学院,广西南宁 530021;广西医科大学基础医学院,广西南宁530021 |
| |
| 基金项目： | 广西壮族自治区自然科学基金，广西医科大学博士启动资金资助，广西壮族自治区中医药管理局中医药科技专项 |
| |
| 摘 要： | 目的 研究两面针根挥发油抗炎、镇痛的药理活性.方法 采用热板法及扭体法实验考察小鼠镇痛作用,应用小鼠耳廓肿胀、脚趾肿胀及棉球肉芽肿胀等实验评价两面针根挥发油的抗炎活性.结果 两面针根挥发油能明显减少小鼠的扭体次数,显著提高小鼠的痛阈值；对二甲苯致小鼠耳廓肿胀、棉球肉芽肿胀实验、角叉菜胶致足趾肿胀实验均有显著的抑制作用.结论 两面针根挥发油有强的抗炎镇痛活性.
|
| 关 键 词： | 两面针根挥发油 抗炎 镇痛 |
Anti - inflammatory and Analgesic Activities of Essential Oil from the Roots of Zanthoxylum nitidum DC. |
| |
| ZHOU Jing-fan
,
QIN Fu-jing
,
FENG Jie
,
WEI Liu-ting.Anti - inflammatory and Analgesic Activities of Essential Oil from the Roots of Zanthoxylum nitidum DC.[J].Lishizhen Medicine and Materia Medica Research,2012,23(1):19-20. |
| |
| Authors: | ZHOU Jing-fan QIN Fu-jing FENG Jie WEI Liu-ting |
| |
| Institution: | 1,2(1.School of Pharmacological Sciences,Guangxi Medical University,Nanning 530021,China;2.School of Preclinical Medicine,Guangxi Medical University,Nanning 530021,China) |
| |
| Abstract: | Objective To study the anti-inflammatory and analgesic activities of essential oil from the roots of Zanthoxylum nitidum. Methods Acetic acid writhing method and hot-plate method were used to study the analgesic activities.Auricle edema induced by dimethylbenzene,cotton pellet granuloma of the mice and edema in feet induced by carrageen were used for anti-inflammatory experiments. Results The essential oil from the roots of Zanthoxylum nitidum inhibited writhing response and enhanced the threshold of pain value significantly.The essential oil inhibited auricle edema induced by dimethylbenzene and edema in feet induced by carrageen significantly.The essential oil significantly inhibited the weight of cotton pellet-induced granuloma formation. Conclusion The essential oil from the roots of Zanthoxylum nitidum shows anti-inflammatory and analgesic activities notably. |
| |
| Keywords: | The roots of Zanthoxylum nitidum Essential oil Anti-inflammatory Analgesic |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
