ANAESTHESIA AND THE RETICULO-ENDOTHELIAL SYSTEM: COMPARISON OF HALOTHANE-NITROUS OXIDE AND NEUROLEPTANALGESIA |
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| Authors: | DOENICKE, A. KROPP, W. |
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| Affiliation: | Abteilung fur Anaesthesie der Chirurgischen Universitatspoliklinik D-8000, Miinchen 2, Pettenkoferstrasse 8a, West Germany |
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| Abstract: | The effect of halothane anaesthesia and neuroleptanalgesia (NLA)on the phagocytic activity of the reticulo-endothelial system(RES) was investigated with the aid of the Lipofundin clearancetest. The results suggest that halothane in nitrous oxide depressesthe phagocytic activity of the RES. NLA did not exert a depressanteffect on the RES function. As it is essential for the bodyto be in a defensive condition to cope adequately with infectionand cancer metastases, care must be taken to ensure that ananaesthetic procedure does not cause additional impairment ofRES function. The results of the investigations suggest thatNLA may have advantages in this respect |
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