初产妇药物流产与人工流产术后对再妊娠影响的对比观察

目的:比较初产妇药物流产后和人工流产术后对再妊娠的影响,为选择合适、安全的流产方式提供临床参考。方法:采用回顾性调查方法对135例有人工流产术史、126例有药物流产史及130例无流产史的初产妇进行比较,观察其妊娠期和分娩期并发症的发生情况以及妊娠结局。结果:妊娠期人流组先兆流产发生率明显高于药流组和无流产组,差异有统计学意义(χ2=14.993,P<0.05),其余并发症的发生率各组间差异无统计学意义(P>0.05)。分娩期人流组产后出血、胎盘粘连和胎盘残留的发生率明显高于药流组和无产组,χ2分别为22.146、12.211、9.387,P值均<0.05,胎儿窘迫的发生率各组间差异无统计学意义(P>0.05)。结论:初产妇药物流产后对再次妊娠影响小于人工流产术后,可考虑作为临床终止早孕的首先选择。

Comparative observation of primiparae undergone drug-induced abortion or artificial abortion on subsequent pregnancy

Objective:To observe the effects of drug-induced abortion or artificial abortion for primiparous women on their subsequent pregnancies for clinical evidence to determine a safe and adequate means for termination of pregnancy.Methods:Retrospective comparative study was performed in 135 primiparae undergone artificial abortion,126 with drug-induced abortion history and 130 primiparity without abortion to examine outcomes of subsequent pregnancy and complications associated with gestation and delivery.Results:Higher incidence of threatened abortion during the gestation period was found in women undergone artificial abortion as compared with those with drug-induced abortion or without abortion history.The difference was significant(χ2 = 14.993,P<0.05),yet the additional complications had statistical difference in the three groups(P>0.05).Similarly,Mothers with a history of artificial abortion had significantly higher incidence of postpartum hemorrhage,placental adherence and residual placenta in labor than those experienced drug-induced abortion or no abortion(χ2 = 22.146,χ2 =12.211,χ2 =9.387,respectively,P<0.05).No statistical difference was observed in the three groups regarding incidence of fetal distress(P>0.05).Conclusion:Drug-induced abortion for primigravidas seem to produce less effects on their subsequent pregnancies than artificial intervention,and may be recommended as first option for terminating early gestation.