| 欧博鼻炎冲剂对变应性鼻炎大鼠IFN-γ、IL-2和IgE调节作用的研究 |
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| 引用本文： | 蒋里明,安杨,李彦华.欧博鼻炎冲剂对变应性鼻炎大鼠IFN-γ、IL-2和IgE调节作用的研究[J].四川中医,2012(3):28-30. |
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| 作者姓名： | 蒋里明 安杨 李彦华 |
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| 作者单位： | [1]新疆医科大学中医学院,新疆乌鲁木齐830054 [2]新疆中医药研究院,新疆乌鲁木齐830009 |
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| 基金项目： | 新疆维吾尔自治区沙依巴克区科学技术计划项目 |
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| 摘 要： | 目的:观察欧博鼻炎冲剂和辛芩颗粒对IL-2、IFN-γ和IgE含量的影响,对比欧博鼻炎冲剂及辛芩颗粒对变应性鼻炎大鼠的疗效。方法:用卵清蛋白致敏大鼠制成变应性鼻炎动物模型,用ELISA方法测定血清中总IgE、IL-2和IFN-γ的水平。结果:空白组、模型组、低剂量组、高剂量组与辛芩颗粒血清中的IFN-γ、IL-2和IgE测定结果均有显著性差异(P<0.05),而中剂量与辛芩颗粒组无显著性差异(P>0.05)。结论:高剂量欧博鼻炎冲剂治疗变应性鼻炎比辛芩颗粒疗效显著。
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| 关 键 词： | 变应性鼻炎 IL-2 IFN-γ IgE 欧博鼻炎冲剂 |
Regulation Effect of O’boBiyanChongji on Expression of IL-2、IFN-γ and IgE in the Experimental Allergic Rhinitis in Rats |
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| JIANG Liming,AN Yang,LI Yanhua.Regulation Effect of O’boBiyanChongji on Expression of IL-2、IFN-γ and IgE in the Experimental Allergic Rhinitis in Rats[J].Journal of Sichuan of Traditional Medicine,2012(3):28-30. |
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| Authors: | JIANG Liming AN Yang LI Yanhua |
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| Institution: | 1.College of Traditional Chinese Medicine,Xinjiang Medical University(Urumqi Sinkiang 830054,China) 2.Research Institute of Traditional Chinese Medicine of Sinkiang(Urumqi Sinkiang 830002,China) |
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| Abstract: | Objective： To observe IL-2,IFN-γand IgE levels of the O’boBiyanChongji and XinQin Granules on allergic rhinitis（AR）,and to contrast the effect of O’boBiyanChongji and XinQin Granules for allergic rhinitis rat.Methods： Egg albumin sensitization made rats animal model of allergic rhinitis.The method of ELISA determined the total IgE,IL-2and IFN-γ content in serum.Results： The results of IFN-γ,IL-2 and IgE in serum of Xinqin granules group were significantly different with the control group,model group,low dose group and high dose group,but had no statistical significance with medium dose group.Conclusion： High dose O’boBiyanChongji is more effective than XinQin Granules to treat allergic rhinitis. |
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| Keywords: | Allergic rhinitis IFN-γ IL-2 IgE O’boBiyanChongji |
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